The Project

The ‘CODE SEPSIS’ project was born with the intention of becoming a reference tool in the Spanish health system, to standardise management for early detection and start of therapeutic measures, as well as monitoring response in those areas where care is provided for this severe clinical event. All with the objective of improving management and diminishing mortality related to this time-dependent clinical process.

Sepsis is the body’s response to any type of infection. It is a generalised inflammatory response that can range from being minimally symptomatic up to causing dysfunction of one or several organs. The intensity of the inflammatory response and the number of organs affected is directly related to mortality which is greater when there is septic shock or multiple organ failure. Its frequency is very high and around 27 million cases a year around the world and close to 140,000 cases in Spain need hospitalization. The incidence is 377 cases per 100,000 inhabitants/year, higher than other such common processes as the 223 for stroke, 208 for ischemic heart disease, or 331 for the most common cancers (lung, breast and prostate). Therefore sepsis is the most frequent and least recognised clinical process in a hospital.

At time-dependent units we consider time is gold in the management of Severe Trauma, time is essential to save myocardial tissue in Acute Coronary Syndrome, and every minute counts in stroke. And in sepsis these concepts are all present as every minute that passes without identifying and starting treatment of sepsis there is more organic dysfunction and mortality associated to the clinical event with the highest incidence of hospital deaths.

In the last few years, treatment guidelines and recommendations for management of patients with severe sepsis have been published, with the best example being the Surviving Sepsis Campaign (SSC) promoted by various international scientific societies. Implementation of this strategy has not been uniform in all healthcare levels or all hospitals. Mortality related to severe sepsis is still high and deaths due to infectious conditions in our society are higher than those caused by other diseases whose urgent attention has been organised by care codes. It is estimated that about 3-4 people die every second due to severe sepsis in the world. Hospital mortality varies between 17 to 55%, but it is estimated that in general, a third of patients with severe sepsis or septic shock die.

This is why the Scientific Societies participating in this ambitious project are promoting the creation of a CODE SEPSIS nationwide, in the various Autonomous Communities and Hospitals. The objective of “CODE SEPSIS” is early detection of patients with severe sepsis (at the various healthcare levels), structured implementation of a set of recommended measures to diagnose, monitor and treat these patients and definition of care indicators that help evaluate compliance with recommendations and outcomes of implementing the code at a local, regional and national level. Optimization of sepsis management is associated to a reduction of healthcare costs, the amount of which currently ranges from €17,000 to €55,000 per case.

Having a “CODE SEPSIS” in our country will mean improved care of our patients and decreased mortality, as well as better use of our limited resources, which is the main objective of all those professionals committed to their care, as this is a public health problem.

Therefore, we invite all healthcare professionals, scientific societies, public and private institutions and all those professionals related to healthcare, to participate in this project, for only with a multidisciplinary approach can we achieve the objectives and implement the necessary changes to improve our management of these patients.

CódigoSepsis Project under the auspices of:
FACME